Severe Flu Season Raises Concerns Over Rare Brain Complications in Kids

Harsh Flu Season Sparks Concerns Over Rare Brain Complications in Children

The United States is experiencing its most intense flu season in 15 years, with federal health officials investigating whether it has led to a rise in rare but life-threatening brain complications in children.

Flu Deaths and Rising Concerns

The Centers for Disease Control and Prevention (CDC) estimates that 19,000 people have died from the flu this winter, including 86 children. Among those child deaths, at least nine experienced serious brain complications. The CDC has now asked state health departments to help determine if there are more such cases.

Flu Shot Effectiveness: Some Good News

Despite the severity of this flu season, flu shots have been effective in preventing hospitalizations. According to preliminary CDC data:

• Vaccinated children were 64% to 78% less likely to be hospitalized.
• Vaccinated adults were 41% to 55% less likely to be hospitalized.

Although flu shots do not always prevent infection, they play a crucial role in reducing severe illness and death. “The vaccine’s main role is to keep you out of the hospital and to keep you alive,” said Dr. William Schaffner, a vaccine expert at Vanderbilt University.

Still, it’s not too late to get vaccinated.
“If you haven’t gotten your flu shot yet, get it because we’re still seeing high flu circulation in most of the country,” urged Dr. Sean O’Leary of the American Academy of Pediatrics.

Brain Complications in Children: What to Watch For

Health officials have warned doctors to be on alert for children with flu symptoms who also experience:

• Seizures
• Hallucinations
• Other neurological symptoms

These signs may indicate influenza-associated encephalopathy or encephalitis, including a more severe subtype called acute necrotizing encephalopathy (ANE). Encephalitis is inflammation of the brain and can lead to long-term neurological issues.

The CDC’s analysis of 1,840 child flu deaths since 2010 found that 166 cases involved neurological complications—most in unvaccinated children. However, it is still unclear whether this season’s cases represent an increase in frequency.

Dr. Keith Van Haren of Stanford Medicine Children’s Health has tracked about 15 severe flu-related encephalopathy cases across the country, with additional suspected cases under review.

What Parents Need to Know

While these complications are rare, parents should seek immediate medical attention if a child with the flu shows:

• Labored breathing
• Unusual behavior or confusion
• Seizures or persistent high fever

“Doctors typically see more neurological complications in severe flu seasons, possibly linked to specific influenza strains,” said Dr. O’Leary. Survivors of these complications may experience long-term seizures or other neurological issues.

Uncertainty Over Next Season’s Flu Vaccine

Meanwhile, vaccine manufacturers are already preparing next winter’s flu shots. However, the Food and Drug Administration (FDA) abruptly canceled a key meeting scheduled for March 13, where experts were supposed to decide on the vaccine’s composition.

Dr. O’Leary emphasized the importance of transparency in vaccine decision-making:
“We have historically worked really hard to get transparency around all of these vaccine discussions.”

The FDA will still make its recommendations in time for manufacturers to produce updated vaccines for the 2025-2026 flu season, according to Andrew Nixon, communications director for the Department of Health and Human Services.

Takeaway: Stay Protected

• Flu vaccines remain the best defense against severe illness and complications.
• Parents should be aware of potential neurological symptoms in children with the flu.
• Despite the uncertainty, next season’s flu vaccine is still in development.

This flu season continues to be severe, but vaccination remains a key tool in protecting both children and adults.

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